Article
Reversible phase variation in the phnE gene, which is required for phosphonate metabolism in Escherichia coli K-12.
Journal of bacteriology - 1 Sept 2004
Iqbal Samina, Parker George, Davidson Helen, Moslehi-Rahmani Elham, Robson Robert L
Abstract excerpt
It is known that Escherichia coli K-12 is cryptic (Phn-) for utilization of methyl phosphonate (MePn) and that Phn+ variants can be selected for growth on MePn as the sole P source. Variants arise from deletion via a possible slip strand mechanism of one of three direct 8-bp repeat sequences in phnE, which restores function to a component of a putative ABC type transporter. Here we show that Phn+ variants are...
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