Article
CPEB1, a novel gene silenced in gastric cancer: a Drosophila approach.
Gut - 1 Aug 2012
Caldeira Joana, Simões-Correia Joana, Paredes Joana, Pinto Marta T, Sousa Sónia, Corso Giovanni, Marrelli Daniele, Roviello Franco, Pereira Paulo S, Weil Dominique, Oliveira Carla, Casares Fernando, Seruca Raquel
Abstract excerpt
BACKGROUND: Gastric cancer (GC) is a highly prevalent disease, being the fourth most common cancer and the second leading cause of cancer-associated deaths worldwide. Although many genes have been implicated in its development, many cases remain genetically unexplained. Hence, there is an urgent need to find new disease-related genes. METHODS: A transgenic Drosophila model was used to screen for novel genes...
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