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Article

Transcription factor binding predictions using TRAP for the analysis of ChIP-seq data and regulatory SNPs.

Nature protocols - 3 Nov 2011

Thomas-Chollier Morgane, Hufton Andrew, Heinig Matthias, O'Keeffe Sean, Masri Nassim El, Roider Helge G, Manke Thomas, Vingron Martin

Abstract excerpt

The transcription factor affinity prediction (TRAP) method calculates the affinity of transcription factors for DNA sequences on the basis of a biophysical model. This method has proven to be useful for several applications, including for determining the putative target genes of a given factor. This protocol covers two other applications: (i) determining which transcription factors have the highest affinity in a...

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PMID: 22051799
DOI: 10.1038/nprot.2011.409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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