Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic heterogeneity in Chinese patients with hepatocyte nuclear factor-1β mutations.

Diabetes research and clinical practice - 1 Jan 2012

Wang Congrong, Zhang Rong, Lu Jingyi, Jiang Feng, Hu Cheng, Zhou Jian, Liu Fang, Zhang Feng, Qin Wen, Li Mei, Ma Xiaojing, Yan Jingbin, Bao Yuqian, Xiang Kunsan, Jia Weiping

Abstract excerpt

AIMS/HYPOTHESIS: The aim of this study was to investigate clinical spectrum of hepatocyte nuclear factor-1β (HNF-1β) mutation in Chinese diabetic patients with renal dysfunction and/or structure abnormalities. MATERIALS AND METHODS: A total of 104 diabetic patients with renal structural abnormalities and/or non-diabetic renal dysfunction were recruited and HNF-1β mutation was screened by direct sequencing....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to C-Peptide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetic Nephropathies

Share to Disease Progression

Share to Hepatocyte Nuclear Factor 1-beta

Share to Heterozygote

Share to Mutation, Missense

Source

Identifiers

PMID: 22051731
DOI: 10.1016/j.diabres.2011.10.007

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic heterogeneity in Chinese patients with hepatocyte nuclear factor-1β mutations.PMID 22051731Read ↗

A case of a novel mutation in HNF1β-related maturity-onset diabetes of the young type 5 with diabetic kidney disease complication in a Chinese family.Semantic proximity Read ↗

From Mutation to Symptoms: A Multi-Center Study on HNF1B-Related Nephropathy in Chinese ChildrenSemantic proximity Read ↗

Effect of mutation at c.493T>C locus of transcription factor HNF1α gene on its protein level.Semantic proximity Read ↗

Three new mutations in the hepatocyte nuclear factor-1alpha gene in Japanese subjects with diabetes mellitus: clinical features and functional characterization.Semantic proximity Read ↗

T130I mutation in HNF-4α gene is a loss-of-function mutation in hepatocytes and is associated with late-onset Type 2 diabetes mellitus in Japanese subjectsSemantic proximity Read ↗

From mutation to symptoms: a multi-center study on HNF1B-related nephropathy in Chinese children.Semantic proximity Read ↗

Genotype-phenotype correlations of fasting C-peptide and lipids in HNF1A-MODY: a single-center series and multi-center cross-sectional analysis in Chinese population.Semantic proximity Read ↗

Common variants of hepatocyte nuclear factor 1beta are associated with type 2 diabetes in a Chinese population.Semantic proximity Read ↗

Functional analyses of the mutation nt-128 T→G in the hepatocyte nuclear factor-1α promoter region in Chinese diabetes pedigrees.Semantic proximity Read ↗

Nonsense and Missense Mutations in the Human Hepatocyte Nuclear Factor-1β Gene (<i>TCF2</i>) and Their Relation to Type 2 Diabetes in JapaneseSemantic proximity Read ↗

Hepatocyte Nuclear Factor 1β-Associated Kidney Disease: More than Renal Cysts and Diabetes.Semantic proximity Read ↗

Mutations in hepatocyte nuclear factor-1β and their related phenotypesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.