Article
Rapid eye movements during sleep in mice: high trait-like stability qualifies rapid eye movement density for characterization of phenotypic variation in sleep patterns of rodents.
BMC neuroscience - 2 Nov 2011
Fulda Stephany, Romanowski Christoph P N, Becker Andreas, Wetter Thomas C, Kimura Mayumi, Fenzel Thomas
Abstract excerpt
BACKGROUND: In humans, rapid eye movements (REM) density during REM sleep plays a prominent role in psychiatric diseases. Especially in depression, an increased REM density is a vulnerability marker for depression. In clinical practice and research measurement of REM density is highly standardized. In basic animal research, almost no tools are available to obtain and systematically evaluate eye movement data,...
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