Article
Control of Plasmodium falciparum erythrocytic cycle: γδ T cells target the red blood cell-invasive merozoites.
Blood - 22 Dec 2011
Costa Giulia, Loizon Séverine, Guenot Marianne, Mocan Iulia, Halary Franck, de Saint-Basile Geneviève, Pitard Vincent, Déchanet-Merville Julie, Moreau Jean-François, Troye-Blomberg Marita, Mercereau-Puijalon Odile, Behr Charlotte
Abstract excerpt
The control of Plasmodium falciparum erythrocytic parasite density is essential for protection against malaria, because it prevents pathogenesis and progression toward severe disease. P falciparum blood-stage parasite cultures are inhibited by human Vγ9Vδ2 γδ T cells, but the underlying mechanism remains poorly understood. Here, we show that both intraerythrocytic parasites and the extracellular red blood...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.