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Article

Patterns of interaction between genetic and nongenetic attributes and methotrexate efficacy in rheumatoid arthritis.

Pharmacogenetics and genomics - 1 Jan 2012

Dervieux Thierry, Wessels Judith A M, Kremer Joel M, Padyukov Leonid, Seddighzadeh Maria, Saevarsdottir Saedis, van Vollenhoven Ronald F, Klareskog Lars, Huizinga Tom W, Guchelaar Henk-Jan

Abstract excerpt

OBJECTIVE: The contribution of low-penetrance single nucleotide polymorphisms to methotrexate efficacy in rheumatoid arthritis (RA) is inconsistent between studies. We sought to elucidate architecture of methotrexate response in three cohorts of patients with RA treated with methotrexate. METHODS...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22044941
DOI: 10.1097/FPC.0b013e32834d3e0b

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22044941-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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