Article
Intrahost passage alters SigB-dependent acid resistance and host cell-associated kinetics of Listeria monocytogenes.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jan 2012
Asakura Hiroshi, Kawamoto Keiko, Okada Yumiko, Kasuga Fumiko, Makino Sou-Ichi, Yamamoto Shigeki, Igimi Shizunobu
Abstract excerpt
Listeria monocytogenes is a foodborne pathogen that causes gastroenteritis, maternofetal infections and meningoencephalitis in humans. Here we report that an intrahost genome mutation alters bacterial acid resistance and the abilities for replication/invasion in tissue cell culture. Among the L. monocytogenes isolates from the recent outbreak in Japan, we found that one food strain, 668, exhibited the greatest...
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