Article
Refractory anemia with ringed sideroblasts associated with marked thrombocytosis (RARS-T), another myeloproliferative condition characterized by JAK2 V617F mutation.
Blood - 1 Oct 2006
Szpurka Hadrian, Tiu Ramon, Murugesan Gurunathan, Aboudola Samer, Hsi Eric D, Theil Karl S, Sekeres Mikkael A, Maciejewski Jaroslaw P
Abstract excerpt
JAK2 V617F mutation recently was identified as a pathogenic factor in typical chronic myeloproliferative diseases (CMPD). Some forms of myelodysplastic syndromes (MDS) show a significant overlap with CMPD (classified as MDS/MPD), but the diagnostic assignment may be challenging. We studied blood or bone marrow from 270 patients with MDS, MDS/MPD, and CMPD for the presence of JAK2 V617F mutation using polymerase...
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