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Article

C21orf91 genotypes correlate with herpes simplex labialis (cold sore) frequency: description of a cold sore susceptibility gene.

The Journal of infectious diseases - 1 Dec 2011

Kriesel John D, Jones Brandt B, Matsunami Nori, Patel Milan K, St Pierre Christine A, Kurt-Jones Evelyn A, Finberg Robert W, Leppert Mark, Hobbs Maurine R

Abstract excerpt

BACKGROUND: Herpes simplex virus type 1 (HSV-1) infects >70% of the United States population. We identified a 3-megabase region on human chromosome 21 containing 6 candidate genes associated with herpes simplex labialis (HSL, "cold sores"). METHODS: We conducted single nucleotide polymorphism (SNP) scans of the chromosome 21 region to define which of 6 possible candidate genes were associated with cold sore...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 21

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Share to Polymorphism, Single Nucleotide

Source

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Identifiers

PMID: 22039568
DOI: 10.1093/infdis/jir633
PMCID: PMC3203230

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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