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Article

Integration host factor is a negative effector of in vivo and in vitro expression of ompC in Escherichia coli.

Journal of bacteriology - 1 Sept 1990

Huang L, Tsui P, Freundlich M

Abstract excerpt

Integration host factor (IHF) of Escherichia coli is a DNA-binding protein involved in gene expression and other cellular functions in E. coli and some of its bacteriophages and plasmids. We report here that IHF is a direct negative effector of the ompC operon of E. coli. IHF binds to ompC DNA and protects a region of 35 base pairs located upstream from the ompC promoters. The addition of IHF to a purified in...

Topics

Bacterial Outer Membrane Proteins
Bacterial Proteins
Base Sequence
Cell Membrane
DNA-Binding Proteins
Deoxyribonuclease I
Escherichia coli
Genotype
Integration Host Factors
Molecular Sequence Data
Operon

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

Protein Binding

Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 2203749
DOI: 10.1128/jb.172.9.5293-5298.1990
PMCID: PMC213192

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2203749-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Integration host factor is a negative effector of in vivo and in vitro expression of ompC in Escherichia coli.PMID 2203749Read ↗

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