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Article

A distant upstream site involved in the negative regulation of the Escherichia coli ompF gene.

Journal of bacteriology - 1 Mar 1994

Huang K J, Schieberl J L, Igo M M

Abstract excerpt

The two-component regulatory system, OmpR-EnvZ, of Escherichia coli K-12 regulates the expression of the major outer membrane porin protein, OmpF. OmpR is a DNA-binding protein which acts as both an activator and a repressor to control ompF transcription. In this article, we describe a new OmpR-binding site that is located between 384 to 351 bp upstream from the ompF start point of transcription. Inactivation of...

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Identifiers

PMID: 8113170
DOI: 10.1128/jb.176.5.1309-1315.1994
PMCID: PMC205194

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A distant upstream site involved in the negative regulation of the Escherichia coli ompF gene.PMID 8113170Read ↗

Mutations in a central highly conserved non-DNA-binding region of OmpR, an Escherichia coli transcriptional activator, influence its DNA-binding ability.Semantic proximity Read ↗

cis-acting ompF mutations that result in OmpR-dependent constitutive expression.Semantic proximity Read ↗

Identification of base pairs important for OmpR-DNA interaction.Semantic proximity Read ↗

Gene activation by the Escherichia coli positive regulator OmpR: a mutational study of the DNA-binding domain of OmpR.Semantic proximity Read ↗

Differential expression of the OmpF and OmpC porin proteins in Escherichia coli K-12 depends upon the level of active OmpR.Semantic proximity Read ↗

The linker region plays an important role in the interdomain communication of the response regulator OmpR.Semantic proximity Read ↗

The DNA-binding domain of OmpR: crystal structures of a winged helix transcription factor.Semantic proximity Read ↗

Gene activation by the Escherichia coli positive regulator, OmpR. Phosphorylation-independent mechanism of activation by an OmpR mutant.Semantic proximity Read ↗

A single amino acid substitution in the C terminus of OmpR alters DNA recognition and phosphorylation.Semantic proximity Read ↗

A phosphorylation site mutant of OmpR reveals different binding conformations at ompF and ompC.Semantic proximity Read ↗

OmpR mutants specifically defective for transcriptional activation.Semantic proximity Read ↗

Mechanism of gene activation by the Escherichia coli positive regulator, OmpR: a mutant defective in transcriptional activation.Semantic proximity Read ↗

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