Article
Mapping cerebellar abiotrophy in Australian Kelpies.
Animal genetics - 1 Dec 2011
Shearman J R, Cook R W, McCowan C, Fletcher J L, Taylor R M, Wilton A N
Abstract excerpt
An autosomal recessive form of cerebellar abiotrophy occurs in Australian Kelpie dogs. Clinical signs range from mild ataxia with intention tremor to severe ataxia with seizures. A whole-genome mapping analysis was performed using Affymetrix Canine SNP array v2 on 11 affected and 19 control dogs, but there was no significant association with disease. A homozygosity analysis identified a three megabase region...
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