Article
HLA and MICA genes in patients with tuberculosis in Brazil.
Tissue antigens - 1 Jan 2012
Souza C F, Noguti E N, Visentainer J E L, Cardoso R F, Petzl-Erler M L, Tsuneto L T
Abstract excerpt
Major histocompatibility complex (MHC) genes have been investigated because of their crucial role in the defense against pathogens and their high degree of polymorphism. We performed a case-control study to assess a genetic association of MHC genes with susceptibility to tuberculosis (TB). The allelic lineages HLA-A*02 and B*18 were significantly less frequent in TB patients (n = 112, 44.6% women) than in...
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