Article
In vivo imaging of intersynaptic vesicle exchange using VGLUT1 Venus knock-in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 26 Oct 2011
Herzog Etienne, Nadrigny Fabien, Silm Katlin, Biesemann Christoph, Helling Imke, Bersot Tiphaine, Steffens Heinz, Schwartzmann Richard, Nägerl U Valentin, El Mestikawy Salah, Rhee JeongSeop, Kirchhoff Frank, Brose Nils
Abstract excerpt
The vesicular glutamate transporter VGLUT1 loads synaptic vesicles with the neurotransmitter glutamate and thereby determines glutamate release at many synapses in the mammalian brain. Due to its function and selective localization, VGLUT1 is one of the most specific markers for glutamatergic synaptic vesicles. It has been used widely to identify glutamatergic synapses, and its expression levels are tightly...
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