Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ectopic PDX-1 Expression Directly Reprograms Human Keratinocytes along Pancreatic Insulin-Producing Cells Fate

18 Oct 2011

Abstract excerpt

BACKGROUND: Cellular differentiation and lineage commitment have previously been considered irreversible processes. However, recent studies have indicated that differentiated adult cells can be reprogrammed to pluripotency and, in some cases, directly into alternate committed lineages. However, although pluripotent cells can be induced in numerous somatic cell sources, it was thought that inducing alternate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Pancreatic function and diabetes
Share to Pluripotent Stem Cells Research
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22028850
DOI: 10.1371/journal.pone.0026298

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ectopic PDX-1 Expression Directly Reprograms Human Keratinocytes along Pancreatic Insulin-Producing Cells FatePMID 22028850Read ↗

Direct reprogramming of human fibroblasts into insulin-producing cells using transcription factorsSemantic proximity Read ↗

Direct reprogramming of human fibroblasts into insulin-producing cells by transcription factorsSemantic proximity Read ↗

Biphasic Induction of Pdx1 in Mouse and Human Embryonic Stem Cells Can Mimic Development of Pancreatic β-CellsSemantic proximity Read ↗

Insulin-Producing Cells Derived from Human Embryonic Stem Cells: Comparison of Definitive Endoderm- and Nestin-Positive Progenitor-Based Differentiation StrategiesSemantic proximity Read ↗

Exendin-4 Promotes Liver Cell Proliferation and Enhances the PDX-1-induced Liver to Pancreas Transdifferentiation ProcessSemantic proximity Read ↗

Long-Term Correction of Diabetes in Mice by In Vivo Reprogramming of Pancreatic DuctsSemantic proximity Read ↗

Single-Cell Gene Expression Analysis of a Human ESC Model of Pancreatic Endocrine Development Reveals Different Paths to β-Cell Differentiation.Semantic proximity Read ↗

Directed Differentiation of Human Embryonic Stem Cells into the Pancreatic Endocrine LineageSemantic proximity Read ↗

Regulated Expression of pdx-1 Promotes In Vitro Differentiation of Insulin-Producing Cells From Embryonic Stem CellsSemantic proximity Read ↗

The Effect of Overexpression of Pdx1 and Foxa2 on the Differentiation of Human Embryonic Stem Cells into Pancreatic CellsSemantic proximity Read ↗

Endodermal differentiation of human pluripotent stem cells to insulin-producing cells in 3D culture.Semantic proximity Read ↗

Regulation of multiple signaling pathways promotes the consistent expansion of human pancreatic progenitors in defined conditionsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.