Article
Polymorphic mutations associated with the emergence of the multinucleoside/tide resistance mutations 69 insertion and Q151M.
Journal of acquired immune deficiency syndromes (1999) - 1 Feb 2012
Scherrer Alexandra U, von Wyl Viktor, Götte Matthias, Klimkait Thomas, Cellerai Cristina, Yerly Sabine, Böni Jürg, Held Leonhard, Ledergerber Bruno, Günthard Huldrych F
Abstract excerpt
BACKGROUND: We hypothesized that polymorphic mutations exist that are associated with the emergence of the multinucleoside resistance mutations (MNR), 69 insertion and Q151M. METHODS: The Swiss HIV Cohort Study was screened, and the frequencies of polymorphic mutations in HIV-1 (subtype B) were compared between patients detected with the 69 insertion (n = 17), Q151M (n = 29), ≥2 thymidine analogue mutations (TAM)...
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