Article
Risk factors and outcomes for the Q151M and T69 insertion HIV-1 resistance mutations in historic UK data.
AIDS research and therapy - 16 Apr 2018
Stirrup Oliver T, Dunn David T, Tostevin Anna, Sabin Caroline A, Pozniak Anton, Asboe David, Cox Alison, Orkin Chloe, Martin Fabiola, Cane Patricia
Abstract excerpt
BACKGROUND: The prevalence of HIV-1 resistance to antiretroviral therapies (ART) has declined in high-income countries over recent years, but drug resistance remains a substantial concern in many low and middle-income countries. The Q151M and T69 insertion (T69i) resistance mutations in the viral reverse transcriptase gene can reduce susceptibility to all nucleoside/tide analogue reverse transcriptase inhibitors,...
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