Article
Reproductive factors and NOS3 variant interactions in primary open-angle glaucoma.
Molecular vision - 1 Jan 2011
Kang Jae Hee, Wiggs Janey L, Haines Jonathan, Abdrabou Wael, Pasquale Louis R
Abstract excerpt
PURPOSE: To investigate whether associations with the nitric oxide synthase gene (NOS3) variants and risk of primary open-angle glaucoma (POAG) depend on female reproductive factors. METHODS: Two functional and two tagging single nucleotide polymorphisms (SNPs; T-786C: rs2070744, Glu298Asp: rs1799983, rs7830, and rs3918188) were evaluated in a nested case-control study from the Nurses' Health Study (women...
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