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Article

PoPoolation2: identifying differentiation between populations using sequencing of pooled DNA samples (Pool-Seq).

Bioinformatics (Oxford, England) - 15 Dec 2011

Kofler Robert, Pandey Ram Vinay, Schlötterer Christian

Abstract excerpt

SUMMARY: Sequencing pooled DNA samples (Pool-Seq) is the most cost-effective approach for the genome-wide comparison of population samples. Here, we introduce PoPoolation2, the first software tool specifically designed for the comparison of populations with Pool-Seq data. PoPoolation2 implements a range of commonly used measures of differentiation (F(ST), Fisher's exact test and Cochran-Mantel-Haenszel test) that...

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Identifiers

PMID: 22025480
DOI: 10.1093/bioinformatics/btr589
PMCID: PMC3232374

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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