Article
Exon 11 mutations, Ki67, and p16(INK4A) as predictors of prognosis in patients with GIST.
Pathology, research and practice - 15 Nov 2011
Cerski Marcelle R, Pereira Fernanda, Matte Ursula S, Oliveira Francine H, Crusius Felipe L, Waengertner Luiz E, Osvaldt Alessandro, Fornari Fernando, Meurer Luise
Abstract excerpt
Prognostic biomarkers for GIST are under investigation. The aim of this study was to assess whether exon 11 mutations, Ki67, and p16(INK4A) are predictors of prognosis in GIST. Consecutive GIST cases (n=84) had their specimens evaluated for exon 11 mutations and expression of Ki67 and p16(INK4A). Surgical cases were categorized according to NIH and Miettinen's classification, and survival was analyzed from...
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