Article
Gene mutations and prognostic factors analysis in extragastrointestinal stromal tumor of a Chinese three-center study.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract - 1 Apr 2011
Zheng Song, Huang Ke-er, Tao De-you, Pan Yue-long
Abstract excerpt
BACKGROUND: Most gastrointestinal stromal tumors (GISTs) have gain-of-function mutation of the c-kit gene, and some have mutation of the platelet-derived growth factor receptor-α (PDGFR-α) gene. Extragastrointestinal stromal tumors (EGISTs) are mesenchymal tumors that occur outside the digestive tract. But the clinicopathologic characteristics of EGISTs are still poorly understood. METHODS: Paraffin-embedded...
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