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Article

Detection of thrombophilic mutations related to spontaneous abortions by a multiplex SNaPshot method.

Genetic testing and molecular biomarkers - 1 Apr 2012

Madjunkova Svetlana, Volk Marija, Peterlin Borut, Plaseska-Karanfilska Dijana

Abstract excerpt

Spontaneous abortion is a significant clinical problem of different etiologies. Certain thrombophilia gene mutations have been associated with an increased risk of spontaneous abortion. Also, mutations in folate-related genes can lead to abnormal chromosomal segregation during meiosis which is the most common cause of spontaneous abortion. We have developed a multiplex single-base extension reaction assay that...

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Share to Abortion, Spontaneous
Share to Electrophoresis, Polyacrylamide Gel

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Factor V

Share to Multiplex Polymerase Chain Reaction

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Share to Pregnancy Complications, Hematologic

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Source

Open in PubMed Open full text

Identifiers

PMID: 22023244
DOI: 10.1089/gtmb.2011.0173
PMCID: PMC3326265

Genes

MTHFR
MTR
MTRR
FGB

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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