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Article

Increased frequency of combined methylenetetrahydrofolate reductase C677T and A1298C mutated alleles in spontaneously aborted embryos.

European journal of human genetics : EJHG - 1 Feb 2002

Zetterberg Henrik, Regland Björn, Palmér Mona, Ricksten Anne, Palmqvist Lars, Rymo Lars, Arvanitis Demetrios A, Spandidos Demetrios A, Blennow Kaj

Abstract excerpt

The pathogenesis of spontaneous abortion is complex, presumably involving the interaction of several genetic and environmental factors. The methylenetetrahydrofolate reductase (MTHFR) gene C677T and A1298C polymorphisms are commonly associated with defects in folate dependent homocysteine metabol...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Embryo, Mammalian

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Mutation, Missense

Share to Oxidoreductases Acting on CH-NH Group Donors

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Source

Identifiers

PMID: 11938441
DOI: 10.1038/sj.ejhg.5200767

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11938441-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Increased frequency of combined methylenetetrahydrofolate reductase C677T and A1298C mutated alleles in spontaneously aborted embryos.PMID 11938441Read ↗

Prevalent genotypes of methylenetetrahydrofolate reductase (MTHFR C677T and A1298C) in spontaneously aborted embryos.Semantic proximity Read ↗

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Maternal methylenetetrahydrofolate reductase (MTHFR) A1298C polymorphism: implications in preventing recurrent pregnancy loss.Semantic proximity Read ↗

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