Article
The MTHFD1 c.1958 G>A polymorphism and recurrent spontaneous abortions.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians - 1 Jan 2011
Crişan Tania O, Trifa Adrian, Farcaş Marius, Militaru Mariela, Netea Mihai, Pop Ioan, Popp Radu
Abstract excerpt
OBJECTIVE: Our aim was to evaluate the possible association between recurrent spontaneous abortions (RSA) and the c.1958 G>A SNP in the MTHFD1 gene encoding a trifunctional enzyme involved in DNA synthesis and folate metabolism. METHODS: By the means of PCR-RFLP we genotyped 131 women with a hist...
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