Article
Outer membrane vesicles of Porphyromonas gingivalis elicit a mucosal immune response.
PloS one - 1 Jan 2011
Nakao Ryoma, Hasegawa Hideki, Ochiai Kuniyasu, Takashiba Shogo, Ainai Akira, Ohnishi Makoto, Watanabe Haruo, Senpuku Hidenobu
Abstract excerpt
We previously reported that mutation of galE in Porphyromonas gingivalis has pleiotropic effects, including a truncated lipopolysaccharide (LPS) O-antigen and deglycosylation of the outer membrane protein OMP85 homolog. In the present study, further analysis of the galE mutant revealed that it produced little or no outer membrane vesicles (OMVs). Using three mouse antisera raised against whole cells of the P....
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