Article
Fimbrial Proteins of <i>Porphyromonas gingivalis</i> Mediate In Vivo Virulence and Exploit TLR2 and Complement Receptor 3 to Persist in Macrophages
1 Aug 2007
Abstract excerpt
Porphyromonas gingivalis is an oral/systemic pathogen implicated in chronic conditions, although the mechanism(s) whereby it resists immune defenses and persists in the host is poorly understood. The virulence of this pathogen partially depends upon expression of fimbriae comprising polymerized fimbrillin (FimA) associated with quantitatively minor proteins (FimCDE). In this study, we show that isogenic mutants...
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