Article
Identification of a novel Porphyromonas gingivalis outer membrane protein, PG534, required for the production of active gingipains.
FEMS microbiology letters - 1 Sept 2010
Saiki Keitarou, Konishi Kiyoshi
Abstract excerpt
Gingipains are secreted endopeptidases important for the virulence and proliferation of Porphyromonas gingivalis; however, their secretion and biogenesis process is not yet fully elucidated. The PG0534 gene of P. gingivalis W83 encodes a novel protein, PG534, of unknown function. In a PG0534 deletion mutant 83K25, the activities of Arg-gingipains (RgpA and RgpB) and Lys-gingipain (Kgp) were reduced to 4-22% of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
