Article
Identification of genomic regions associated with phenotypic variation between dog breeds using selection mapping.
PLoS genetics - 1 Oct 2011
Vaysse Amaury, Ratnakumar Abhirami, Derrien Thomas, Axelsson Erik, Rosengren Pielberg Gerli, Sigurdsson Snaevar, Fall Tove, Seppälä Eija H, Hansen Mark S T, Lawley Cindy T, Karlsson Elinor K, Bannasch Danika, Vilà Carles, Lohi Hannes, Galibert Francis, Fredholm Merete, Häggström Jens, Hedhammar Ake, André Catherine, Lindblad-Toh Kerstin, Hitte Christophe, Webster Matthew T
Abstract excerpt
The extraordinary phenotypic diversity of dog breeds has been sculpted by a unique population history accompanied by selection for novel and desirable traits. Here we perform a comprehensive analysis using multiple test statistics to identify regions under selection in 509 dogs from 46 diverse breeds using a newly developed high-density genotyping array consisting of >170,000 evenly spaced SNPs. We first identify...
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