Article
Tracking footprints of artificial selection in the dog genome.
Proceedings of the National Academy of Sciences of the United States of America - 19 Jan 2010
Akey Joshua M, Ruhe Alison L, Akey Dayna T, Wong Aaron K, Connelly Caitlin F, Madeoy Jennifer, Nicholas Thomas J, Neff Mark W
Abstract excerpt
The size, shape, and behavior of the modern domesticated dog has been sculpted by artificial selection for at least 14,000 years. The genetic substrates of selective breeding, however, remain largely unknown. Here, we describe a genome-wide scan for selection in 275 dogs from 10 phenotypically diverse breeds that were genotyped for over 21,000 autosomal SNPs. We identified 155 genomic regions that possess strong...
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