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Article

Loss of ASP but not ROPN1 reduces mammalian ciliary motility.

Cytoskeleton (Hoboken, N.J.) - 1 Jan 2012

Fiedler Sarah E, Sisson Joseph H, Wyatt Todd A, Pavlik Jacqueline A, Gambling Todd M, Carson Johnny L, Carr Daniel W

Abstract excerpt

Protein kinase A (PKA) signaling is targeted by interactions with A-kinase anchoring proteins (AKAPs) via a dimerization/docking domain on the regulatory (R) subunit of PKA. Four other mammalian proteins [AKAP-associated sperm protein (ASP), ropporin (ROPN1), sperm protein 17 (SP17) and calcium binding tyrosine-(Y)-phosphorylation regulated protein (CABYR)] share this highly conserved RII dimerization/docking...

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Topics

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Share to Adaptor Proteins, Signal Transducing
Share to Cilia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclic AMP-Dependent Protein Kinases

Share to Membrane Proteins

Share to Mice, Mutant Strains

Share to rho GTP-Binding Proteins

Share to Sperm Motility

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Source

Open in PubMed Open full text

Identifiers

PMID: 22021175
DOI: 10.1002/cm.20539
PMCID: PMC3261315

Genes

ROPN1
CABYR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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