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Article

Controlled release from multilayer silk biomaterial coatings to modulate vascular cell responses.

Biomaterials - 1 Mar 2008

Wang Xianyan, Zhang Xiaohui, Castellot John, Herman Ira, Iafrati Mark, Kaplan David L

Abstract excerpt

A multilayered silk fibroin protein coating system was employed as a drug carrier and delivery system to evaluate vascular cell responses to heparin, paclitaxel, and clopidogrel. The results demonstrated that the silk coating system was an effective system for drug-eluting coatings, such as for stent applications, based on its useful micromechanical properties and biological outcomes. Cell attachment and...

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Identifiers

PMID: 18048096
DOI: 10.1016/j.biomaterials.2007.10.055
PMCID: PMC2693052

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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