Article
Differential repair of UV damage in rad mutants of Saccharomyces cerevisiae: a possible function of G2 arrest upon UV irradiation.
Molecular and cellular biology - 1 Sept 1990
Terleth C, Schenk P, Poot R, Brouwer J, van de Putte P
Abstract excerpt
After UV irradiation, the transcriptionally active MAT alpha locus in Saccharomyces cerevisiae is preferentially repaired compared with the inactive HML alpha locus. The effect of rad mutations from three different epistasis groups on differential repair was investigated. Three mutants, rad9, rad16, and rad24, were impaired in the removal of UV dimers from the inactive HML alpha locus, whereas they had generally...
Topics
- Blotting, Southern
- DNA Damage
- DNA Repair
- DNA, Fungal
- Genes, Fungal
- Genotype
- Interphase
- Kinetics
- Mutation
- Saccharomyces cerevisiae
- Time Factors
