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Article

Tc, an unusual promoter element required for constitutive transcription of the yeast HIS3 gene.

Molecular and cellular biology - 1 Sept 1990

Mahadevan S, Struhl K

Abstract excerpt

Tc is the proximal promoter element required for constitutive his3 transcription that occurs in the absence of the canonical TATA element (TR) and is initiated from the +1 site. The TC element, unlike TR, does not respond to transcriptional stimulation by the GCN4 or GAL4 activator protein. Analysis of deletion, substitution, and point mutations indicates that Tc mapped between nucleotides -54 and -83 and is a...

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Identifiers

PMID: 2201891
DOI: 10.1128/mcb.10.9.4447-4455.1990
PMCID: PMC361030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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