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Article

Cell adhesion molecules contribute to Alzheimer's disease: multiple pathway analyses of two genome-wide association studies.

Journal of neurochemistry - 1 Jan 2012

Liu Guiyou, Jiang Yongshuai, Wang Ping, Feng Rennan, Jiang Nan, Chen Xiaoyun, Song Hui, Chen Zugen

Abstract excerpt

Alzheimer's disease (AD) is a kind of complex neurological disorder. The complex genetic architecture of AD makes genetic analysis difficult. Fortunately, a pathway-based method to study the existing genome-wide association studies datasets has been applied into AD. However, no shared Kyoto Encyclopaedia of Genes and Genomes (KEGG) pathway was reported. In this study, we performed multiple pathway analyses of...

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PMID: 22017384
DOI: 10.1111/j.1471-4159.2011.07547.x

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