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Analyzing the genes related to Alzheimer's disease via a network and pathway-based approach.

Alzheimer's research & therapy - 27 Apr 2017

Hu Yan-Shi, Xin Juncai, Hu Ying, Zhang Lei, Wang Ju

Abstract excerpt

BACKGROUND: Our understanding of the molecular mechanisms underlying Alzheimer's disease (AD) remains incomplete. Previous studies have revealed that genetic factors provide a significant contribution to the pathogenesis and development of AD. In the past years, numerous genes implicated in this disease have been identified via genetic association studies on candidate genes or at the genome-wide level. However,...

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PMID: 28446202
DOI: 10.1186/s13195-017-0252-z
PMCID: PMC5406904

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