Article
Aneurysm-Specific miR-221 and miR-146a Participates in Human Thoracic and Abdominal Aortic Aneurysms.
International journal of molecular sciences - 20 Apr 2017
Venkatesh Premakumari, Phillippi Julie, Chukkapalli Sasanka, Rivera-Kweh Mercedes, Velsko Irina, Gleason Thomas, VanRyzin Paul, Aalaei-Andabili Seyed Hossein, Ghanta Ravi Kiran, Beaver Thomas, Chan Edward Kar Leung, Kesavalu Lakshmyya
Abstract excerpt
Altered microRNA expression is implicated in cardiovascular diseases. Our objective was to determine microRNA signatures in thoracic aortic aneurysms (TAAs) and abdominal aortic aneurysms (AAAs) compared with control non-aneurysmal aortic specimens. We evaluated the expression of fifteen selected microRNA in human TAA and AAA operative specimens compared to controls. We observed significant upregulation of...
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