Article
Unbiased Profile of MicroRNA Expression in Ascending Aortic Aneurysm Tissue Appoints Molecular Pathways Contributing to the Pathology.
The Annals of thoracic surgery - 1 Oct 2016
Licholai Sabina, Blaż Michal, Kapelak Boguslaw, Sanak Marek
Abstract excerpt
BACKGROUND: Complex etiopathogenesis of ascending aortic aneurysm suggests contribution of epigenetic mechanisms in its development. Several studies appointed microRNAs (miRs) as essential epigenetic factors in various human diseases; however, little is known about their role in ascending aortic aneurysm. Therefore, the aim of this study was to perform unbiased molecular screening of miRs expression in aneurysmal...
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