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Article

MicroRNA expression signature in human abdominal aortic aneurysms

15 Jun 2012

Abstract excerpt

BACKGROUND: Abdominal aortic aneurysm (AAA) is a dilatation of the aorta affecting most frequently elderly men. Histologically AAAs are characterized by inflammation, vascular smooth muscle cell apoptosis, and extracellular matrix degradation. The mechanisms of AAA formation, progression, and rupture are currently poorly understood. A previous mRNA expression study revealed a large number of differentially...

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PMID: 22704053
DOI: 10.1186/1755-8794-5-25

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