Article
Association between adolescent idiopathic scoliosis with double curve and polymorphisms of calmodulin1 gene/estrogen receptor-α gene.
Orthopaedic surgery - 1 Aug 2009
Zhao Dong, Qiu Gui-xing, Wang Yi-peng, Zhang Jian-guo, Shen Jian-xiong, Wu Zhi-hong
Abstract excerpt
OBJECTIVE: To investigate whether single nucleotide polymorphisms (SNP) of the calmodulin1 (CALM1) and estrogen receptor-α genes correlate with double curve in adolescent idiopathic scoliosis (AIS). METHODS: A total of 67 Chinese patients with AIS with double curve and 100 healthy controls were recruited. Curve pattern and Cobb angle of each patient were recorded. The Cobb angle is at least 30°. There were 60...
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