Article
Association of calmodulin1 gene polymorphisms with susceptibility to adolescent idiopathic scoliosis.
Orthopaedic surgery - 1 Feb 2009
Zhao Dong, Qiu Gui-xing, Wang Yi-peng, Zhang Jian-guo, Shen Jian-xiong, Wu Zhi-hong, Wang Hai
Abstract excerpt
OBJECTIVE: To investigate whether: (i) rs12885713 (-16C > T) and rs5871 polymorphisms in the Calmodulin1 (CALM1) gene are predisposing factors for adolescent idiopathic scoliosis (AIS); and (ii) different single nucleotide polymorphisms (SNP) correlate with different subtypes of AIS. METHODS: A total of 100 AIS patients with Cobb angle above 30° were recruited for this study together with 100 healthy controls....
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