Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Glial connexin expression and function in the context of Alzheimer's disease.

Biochimica et biophysica acta - 1 Aug 2012

Koulakoff Annette, Mei Xin, Orellana Juan A, Sáez Juan C, Giaume Christian

Abstract excerpt

A hallmark of neurodegenerative diseases is the reactive gliosis characterized by a phenotypic change in astrocytes and microglia. This glial response is associated with modifications in the expression and function of connexins (Cxs), the proteins forming gap junction channels and hemichannels. I...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloid beta-Peptides
Share to Astrocytes
Share to Connexins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gap Junctions

Share to Gliosis

Share to Microglia

Share to Neuroglia

Share to Neurons

Source

Identifiers

PMID: 22008509
DOI: 10.1016/j.bbamem.2011.10.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22008509-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Glial connexin expression and function in the context of Alzheimer's disease.PMID 22008509Read ↗

Glial Connexins and Pannexins in the Healthy and Diseased BrainSemantic proximity Read ↗

GJA1 (connexin43) is a key regulator of Alzheimer’s disease pathogenesisSemantic proximity Read ↗

Turning microglia neuroprotective: Towards connexin43-specific therapy of Alzheimer’s diseaseSemantic proximity Read ↗

Pathological phenotypes of astrocytes in Alzheimer's disease.Semantic proximity Read ↗

Gap junction communication in myelinating glia.Semantic proximity Read ↗

Role of Impaired Astrocyte Gap Junction Coupling in Epilepto-GenesisSemantic proximity Read ↗

An Overview of Astrocyte Responses in Genetically Induced Alzheimer’s Disease Mouse ModelsSemantic proximity Read ↗

Purinergic Signaling Participates in a Transition Between Functional States of Reactive Microglia and Controls Astrocyte-Driven Neuroinflammation in the Model of Trimethyltin-Induced NeurodegenerationSemantic proximity Read ↗

Astrocytic transporters in Alzheimer's diseaseSemantic proximity Read ↗

Connexin26 expression in brain parenchymal cells demonstrated by targeted connexin ablation in transgenic miceSemantic proximity Read ↗

Astrocyte dysfunction in temporal lobe epilepsy: K+ channels and gap junction coupling.Semantic proximity Read ↗

Mechanisms of Diseases Associated with Mutation in GJC2/Connexin 47.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.