Article
Genotyping non-small cell lung cancer (NSCLC) in Latin America.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Nov 2011
Arrieta Oscar, Cardona Andrés Felipe, Federico Bramuglia Guillermo, Gallo Aly, Campos-Parra Alma D, Serrano Silvia, Castro Marcelo, Avilés Alejandro, Amorin Edgar, Kirchuk Ricardo, Cuello Mauricio, Borbolla José, Riemersma Omar, Becerra Henry, Rosell Rafael
Abstract excerpt
INTRODUCTION: Frequency of mutations in EGFR and KRAS in non-small cell lung cancer (NSCLC) is different between ethnic groups; however, there is no information in Latin-American population. METHODS: A total of 1150 biopsies of NSCLC patients from Latin America (Argentina, Colombia, Peru, and Mexico) were used extracting genomic DNA to perform direct sequencing of EGFR gene (exons 18 and 21) and KRAS gene in 650...
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