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Article

EGFR mutations in US Hispanic versus non-Hispanic white patients with lung adenocarcinoma.

Archives of pathology & laboratory medicine - 1 Apr 2014

Zhang Wei, McQuitty Elizabeth B, Olsen Randall, Fan Hongxin, Hendrickson Heather, Tio Fermin O, Newton Keith, Cagle Philip T, Jagirdar Jaishree

Abstract excerpt

CONTEXT: Lung cancer is the leading cause of cancer deaths worldwide. First-generation tyrosine kinase inhibitors improve progression-free survival in lung cancers with epidermal growth factor receptor (EGFR) mutations. EGFR mutations occur predominantly in exons 19 and 21 in lung adenocarcinomas of Asians (∼30%), whites (∼15%), and African Americans (∼19%). However, minimal information exists on the prevalence...

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Identifiers

PMID: 23937608
DOI: 10.5858/arpa.2013-0311-OA

Genes

EGFR

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