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Article

Genetic defects in folate and cobalamin pathways affecting the brain.

Clinical chemistry and laboratory medicine - 1 Jan 2013

Kirsch Susanne H, Herrmann Wolfgang, Obeid Rima

Abstract excerpt

Folate and cobalamin are necessary for early brain development and function. Deficiency of folate or cobalamin during pregnancy can cause severe malformation in the central nervous system such as neural tube defects. After birth, folate and cobalamin deficiency can cause anemia, failure to thrive, recurrent infections, psychiatric and neurological symptoms. The folate and the homocysteine metabolic pathways...

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Identifiers

PMID: 23183749
DOI: 10.1515/cclm-2012-0673

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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