Article
ANKK1/DRD2 locus variants are associated with rimonabant efficacy in aiding smoking cessation: pilot data.
Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Dec 2011
Wilcox Charles S, Noble Ernest P, Oskooilar Nader
Abstract excerpt
BACKGROUND: Polymorphism of the DRD2 gene (rs1800497), previously termed Taq1A, includes the A1 and A2 alleles. The A1⁺ genotype (A1/A1, A1/A2) has been associated with smoking dependence. The present study determined which polymorphism of the DRD2 gene had a salutary outcome in administration of rimonabant, a drug used in smoking cessation and obesity studies. METHODS: Seventy-six (76) smokers enrolled into a...
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