Article
Molecular markers of Plasmodium falciparum drug resistance in southern highland Rwanda.
Acta tropica - 1 Jan 2012
Zeile Irene, Gahutu Jean-Bosco, Shyirambere Cyprien, Steininger Christian, Musemakweri Andre, Sebahungu Fidèle, Karema Corine, Harms Gundel, Eggelte Teunis A, Mockenhaupt Frank P
Abstract excerpt
In Rwanda, frequent mutations in the pfdhfr and pfdhps genes of Plasmodium falciparum have suggested intense sulfadoxine-pyrimethamine resistance. However, data on pfmdr1 are not available but might be important in the context of the first-line treatment with artemether-lumefantrine. During a survey among 749 children under five years of age in southern highland Rwanda, 104 P. falciparum isolates were obtained....
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