Article
An experimentally-supported genome-scale metabolic network reconstruction for Yersinia pestis CO92.
BMC systems biology - 13 Oct 2011
Charusanti Pep, Chauhan Sadhana, McAteer Kathleen, Lerman Joshua A, Hyduke Daniel R, Motin Vladimir L, Ansong Charles, Adkins Joshua N, Palsson Bernhard O
Abstract excerpt
BACKGROUND: Yersinia pestis is a gram-negative bacterium that causes plague, a disease linked historically to the Black Death in Europe during the Middle Ages and to several outbreaks during the modern era. Metabolism in Y. pestis displays remarkable flexibility and robustness, allowing the bacterium to proliferate in both warm-blooded mammalian hosts and cold-blooded insect vectors such as fleas. RESULTS: Here...
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