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Article

Exploring the metabolic network of the epidemic pathogen Burkholderia cenocepacia J2315 via genome-scale reconstruction.

BMC systems biology - 25 May 2011

Fang Kechi, Zhao Hansheng, Sun Changyue, Lam Carolyn M C, Chang Suhua, Zhang Kunlin, Panda Gurudutta, Godinho Miguel, Martins dos Santos Vítor A P, Wang Jing

Abstract excerpt

BACKGROUND: Burkholderia cenocepacia is a threatening nosocomial epidemic pathogen in patients with cystic fibrosis (CF) or a compromised immune system. Its high level of antibiotic resistance is an increasing concern in treatments against its infection. Strain B. cenocepacia J2315 is the most infectious isolate from CF patients. There is a strong demand to reconstruct a genome-scale metabolic network of B....

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PMID: 21609491
DOI: 10.1186/1752-0509-5-83
PMCID: PMC3123600

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