Article
Sortase A substrate specificity in GBS pilus 2a cell wall anchoring.
PloS one - 1 Jan 2011
Necchi Francesca, Nardi-Dei Vincenzo, Biagini Massimiliano, Assfalg Michael, Nuccitelli Annalisa, Cozzi Roberta, Norais Nathalie, Telford John L, Rinaudo C Daniela, Grandi Guido, Maione Domenico
Abstract excerpt
Streptococcus agalactiae, also referred to as Group B Streptococcus (GBS), is one of the most common causes of life-threatening bacterial infections in infants. In recent years cell surface pili have been identified in several Gram-positive bacteria, including GBS, as important virulence factors and promising vaccine candidates. In GBS, three structurally distinct types of pili have been discovered (pilus 1, 2a...
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